Tuesday, October 25, 2016

Altazine Moisture Relief Eye Drops


Pronunciation: teh-trah-high-DRAHZ-ah-leen
Generic Name: Tetrahydrozoline
Brand Name: Examples include Altazine Moisture Relief and Visine


Altazine Moisture Relief Eye Drops are used for:

Relieving redness due to minor eye irritation.


Altazine Moisture Relief Eye Drops are a decongestant. It works by constricting swollen blood vessels in the eye, which reduces redness. Irritants cause blood vessels to swell.


Contact your doctor or health care provider immediately if any of these apply to you.


Do NOT use Altazine Moisture Relief Eye Drops if:


  • you are allergic to any ingredient in Altazine Moisture Relief Eye Drops

  • you are taking furazolidone or have taken a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.



Before using Altazine Moisture Relief Eye Drops:


Some medical conditions may interact with Altazine Moisture Relief Eye Drops. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

  • if you have narrow-angle glaucoma, an overactive thyroid, or high blood pressure

Some MEDICINES MAY INTERACT with Altazine Moisture Relief Eye Drops. Tell your health care provider if you are taking any other medicines, especially any of the following:


  • Furazolidone and MAO inhibitors (eg, phenelzine) because side effects, such as headache, high blood pressure, and elevated body temperature, may occur

  • Tricyclic antidepressants (eg, amitriptyline) because they may decrease Altazine Moisture Relief Eye Drops's effectiveness

  • Bromocriptine or catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone, St. John's wort) because their actions and side effects may be increased by Altazine Moisture Relief Eye Drops

This may not be a complete list of all interactions that may occur. Ask your health care provider if Altazine Moisture Relief Eye Drops may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Altazine Moisture Relief Eye Drops:


Use Altazine Moisture Relief Eye Drops as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Altazine Moisture Relief Eye Drops are for use in the eye only. Avoid contact with mucous membranes.

  • If you wear contact lenses, remove them before using Altazine Moisture Relief Eye Drops.

  • To use Altazine Moisture Relief Eye Drops, wash your hands. Tilt your head back. Using your index finger, pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close your eyes. Immediately use your finger to apply pressure to the inside corner of the eye and continue to apply pressure for 1 to 2 minutes after using the medicine. Do not blink.

  • Remove excess medicine around your eye with a clean tissue, being careful not to touch your eye.

  • Wash your hands to remove any medicine that may be on them. To prevent germs from contaminating your medicine, do not touch the applicator tip to any surface, including your eye.

  • Keep the container tightly closed.

  • Do not use Altazine Moisture Relief Eye Drops if solution changes color or becomes cloudy.

  • If you miss a dose of Altazine Moisture Relief Eye Drops and you are using it regularly, use it as soon as possible. If it is much more than 1 hour since your missed dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Altazine Moisture Relief Eye Drops.



Important safety information:


  • Altazine Moisture Relief Eye Drops may cause blurred vision. Do not drive, operate machinery, or do anything else that could be dangerous unless you can see clearly.

  • Do not use Altazine Moisture Relief Eye Drops for longer than 3 days without checking with your doctor.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Using too much of Altazine Moisture Relief Eye Drops may increase redness of the eye.

  • Altazine Moisture Relief Eye Drops are not recommended for use in CHILDREN younger than 6 years of age. Safety and effectiveness in this age group have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Altazine Moisture Relief Eye Drops during pregnancy. It is unknown if Altazine Moisture Relief Eye Drops are excreted in breast milk. If you are or will be breast-feeding while you are using Altazine Moisture Relief Eye Drops, check with your doctor or pharmacist to discuss the risks to your baby.


Possible side effects of Altazine Moisture Relief Eye Drops:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Blurring, tearing, or stinging of the eye; dilation of pupils.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in vision; continued redness or irritation of the eye; eye pain; headache.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Altazine Moisture Relief side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Altazine Moisture Relief Eye Drops may be harmful if swallowed, especially in children.


Proper storage of Altazine Moisture Relief Eye Drops:

Store Altazine Moisture Relief Eye Drops at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Altazine Moisture Relief Eye Drops out of the reach of children and away from pets.


General information:


  • If you have any questions about Altazine Moisture Relief Eye Drops, please talk with your doctor, pharmacist, or other health care provider.

  • Altazine Moisture Relief Eye Drops are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Altazine Moisture Relief Eye Drops. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Altazine Moisture Relief resources


  • Altazine Moisture Relief Side Effects (in more detail)
  • Altazine Moisture Relief Use in Pregnancy & Breastfeeding
  • Altazine Moisture Relief Drug Interactions
  • Altazine Moisture Relief Support Group
  • 0 Reviews for Altazine Moisture Relief - Add your own review/rating


Compare Altazine Moisture Relief with other medications


  • Eye Dryness/Redness

Monday, October 24, 2016

Avalide



Generic Name: hydrochlorothiazide and irbesartan (HYE droe KLOR oh THYE a zide and ir be SAR tan)

Brand Names: Avalide


What is hydrochlorothiazide and irbesartan?

Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention.


Irbesartan is an angiotensin II receptor antagonist. Irbesartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.


The combination of hydrochlorothiazide and irbesartan is used to treat high blood pressure (hypertension).


Hydrochlorothiazide and irbesartan may also be used for purposes not listed in this medication guide.


What is the most important information I should know about hydrochlorothiazide and irbesartan?


Do not use hydrochlorothiazide and irbesartan if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. You should not use this medication if you are allergic to irbesartan or hydrochlorothiazide (Carozide, Diaqua, Ezide HCTZ, HydroDiuril, Microzide, and others), or if you are unable to urinate. Drinking alcohol can further lower your blood pressure and may increase certain side effects of hydrochlorothiazide and irbesartan. In rare cases, hydrochlorothiazide and irbesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine.

What should I discuss with my healthcare provider before taking hydrochlorothiazide and irbesartan?


You should not use this medication if you are allergic to irbesartan or hydrochlorothiazide (Carozide, Diaqua, Ezide HCTZ, HydroDiuril, Microzide, and others), or if you are unable to urinate.

To make sure you can safely take hydrochlorothiazide and irbesartan, tell your doctor if you have any of these other conditions:


  • kidney disease;

  • liver disease;


  • congestive heart failure;




  • glaucoma;




  • low or high levels of potassium in your blood;




  • asthma or allergies;




  • high cholesterol or triglyceride levels;




  • gout;




  • lupus;




  • diabetes; or




  • an allergy to sulfa drugs or penicillin.




FDA pregnancy category D. Do not use hydrochlorothiazide and irbesartan if you are pregnant. Stop using this medication and tell your doctor right away if you become pregnant. Irbesartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester. Use effective birth control while taking hydrochlorothiazide and irbesartan. It is not known whether hydrochlorothiazide and irbesartan passes into breast milk or if it could harm a nursing baby. You should not breast-feed while you are using hydrochlorothiazide and irbesartan.

How should I take hydrochlorothiazide and irbesartan?


Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.


Your doctor may occasionally change your dose to make sure you get the best results.


Your blood pressure will need to be checked often. Visit your doctor regularly.


Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.

Hydrochlorothiazide can interfere with the results of a thyroid test. Tell any doctor who treats you that you are using this medication.


It may take up to 4 weeks for this medication to control your blood pressure. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life. If you need surgery, tell the surgeon ahead of time that you are using hydrochlorothiazide and irbesartan. You may need to stop using the medicine for a short time. Store at room temperature away from moisture and heat.

What happens if I miss a dose?


Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast or slow heartbeat, feeling light-headed, or fainting.


What should I avoid while taking hydrochlorothiazide and irbesartan?


Drinking alcohol can further lower your blood pressure and may increase certain side effects of hydrochlorothiazide and irbesartan.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Follow your doctor's instructions about the type and amount of liquids you should drink. In some cases, drinking too much liquid can be as unsafe as not drinking enough.


Do not use potassium supplements or salt substitutes while you are taking hydrochlorothiazide and irbesartan, unless your doctor has told you to.

Hydrochlorothiazide and irbesartan side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. In rare cases, hydrochlorothiazide and irbesartan can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have muscle pain, tenderness, or weakness especially if you also have fever, nausea or vomiting, and dark colored urine. Call your doctor at once if you have any other serious side effects, such as:

  • eye pain, vision problems;




  • feeling like you might pass out;




  • chest pain, feeling short of breath, even with mild exertion;




  • fever;




  • swelling, rapid weight gain;




  • urinating more or less than usual, or not at all;




  • jaundice (yellowing of the skin or eyes); or




  • dry mouth, increased thirst, drowsiness, restless feeling, confusion, increased urination, fast heart rate, feeling light-headed, fainting, or seizure (convulsions).



Less serious side effects may include:



  • stomach pain, heartburn;




  • muscle pain;




  • dizziness, drowsiness;




  • headache;




  • runny or stuffy nose, sore throat; or




  • dry cough.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect hydrochlorothiazide and irbesartan?


Tell your doctor about all other medicines you use, especially:



  • any other diuretics or blood pressure medications;




  • steroids (prednisone and others);




  • lithium (Eskalith, Lithobid);




  • cholestyramine (Prevalite, Questran) or colestipol (Colestid);




  • insulin or oral diabetes medications;




  • a barbiturate such as amobarbital (Amytal), butabarbital (Butisol), mephobarbital (Mebaral), secobarbital (Seconal), or phenobarbital (Luminal, Solfoton);




  • aspirin or other NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve, Naprosyn, Naprelan, Treximet), celecoxib (Celebrex), diclofenac (Arthrotec, Cambia, Cataflam, Voltaren, Flector Patch, Pennsaid, Solareze), indomethacin (Indocin), meloxicam (Mobic), and others;




  • a muscle relaxer such as baclofen (Lioresal), carisoprodol (Soma), cyclobenzaprine (Flexeril), dantrolene (Dantrium), metaxalone (Skelaxin), or methocarbamol (Robaxin), orphenadrine (Norflex), or tizanidine (Zanaflex); or




  • a narcotic medication such as hydrocodone (Lortab, Vicodin), meperidine (Demerol), methadone (Methadose), oxycodone (OxyContin), propoxyphene (Darvon, Darvocet), and others.



This list is not complete and other drugs may interact with hydrochlorothiazide and irbesartan. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Avalide resources


  • Avalide Side Effects (in more detail)
  • Avalide Use in Pregnancy & Breastfeeding
  • Drug Images
  • Avalide Drug Interactions
  • Avalide Support Group
  • 4 Reviews for Avalide - Add your own review/rating


  • Avalide Prescribing Information (FDA)

  • Avalide Advanced Consumer (Micromedex) - Includes Dosage Information

  • Avalide MedFacts Consumer Leaflet (Wolters Kluwer)

  • Avalide Consumer Overview



Compare Avalide with other medications


  • High Blood Pressure


Where can I get more information?


  • Your pharmacist can provide more information about hydrochlorothiazide and irbesartan.

See also: Avalide side effects (in more detail)


Loderm




Loderm may be available in the countries listed below.


Ingredient matches for Loderm



Erythromycin

Erythromycin laurilsulfate (a derivative of Erythromycin) is reported as an ingredient of Loderm in the following countries:


  • Spain

International Drug Name Search

Hemabate




In the US, Hemabate (carboprost systemic) is a member of the drug class uterotonic agents and is used to treat Abortion and Postpartum Bleeding.

US matches:

  • Hemabate

UK matches:

  • Hemabate Sterile Solution
  • Hemabate Sterile Solution (SPC)

Ingredient matches for Hemabate



Carboprost

Carboprost tromethamine (a derivative of Carboprost) is reported as an ingredient of Hemabate in the following countries:


  • Canada

  • China

  • Taiwan

  • United Kingdom

  • United States

International Drug Name Search

Glossary

SPC Summary of Product Characteristics (UK)

Click for further information on drug naming conventions and International Nonproprietary Names.

Effect




Effect may be available in the countries listed below.


Ingredient matches for Effect



Paracetamol

Paracetamol is reported as an ingredient of Effect in the following countries:


  • Slovakia

International Drug Name Search

Inova 4/1 Acne Control Therapy Pads


Pronunciation: BEN-zoe-il/SAL-i-SIL-ik
Generic Name: Benzoyl Peroxide/Salicylic Acid
Brand Name: Inova 4/1 Acne Control Therapy


Inova 4/1 Acne Control Therapy Pads are used for:

Treating acne.


Inova 4/1 Acne Control Therapy Pads are a keratolytic agent with antibacterial actions. It works by killing bacteria that cause acne. It also has mild drying and peeling activity on the skin.


Do NOT use Inova 4/1 Acne Control Therapy Pads if:


  • you are allergic to any ingredient in Inova 4/1 Acne Control Therapy Pads

Contact your doctor or health care provider right away if any of these apply to you.



Before using Inova 4/1 Acne Control Therapy Pads:


Some medical conditions may interact with Inova 4/1 Acne Control Therapy Pads. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:


  • if you are pregnant, planning to become pregnant, or are breast-feeding

  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

  • if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Inova 4/1 Acne Control Therapy Pads. However, no specific interactions with Inova 4/1 Acne Control Therapy Pads are known at this time.


Ask your health care provider if Inova 4/1 Acne Control Therapy Pads may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.


How to use Inova 4/1 Acne Control Therapy Pads:


Use Inova 4/1 Acne Control Therapy Pads as directed by your doctor. Check the label on the medicine for exact dosing instructions.


  • Wash the affected area with a mild cleanser and water before applying Inova 4/1 Acne Control Therapy Pads.

  • Apply Inova 4/1 Acne Control Therapy Pads as directed. Cover all the affected areas.

  • Do not apply Inova 4/1 Acne Control Therapy Pads to raw, inflamed, damaged, or irritated skin, including sunburns. Do not apply to open wounds.

  • Wash your hands immediately after using Inova 4/1 Acne Control Therapy Pads.

  • If you miss a dose of Inova 4/1 Acne Control Therapy Pads, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Inova 4/1 Acne Control Therapy Pads.



Important safety information:


  • Inova 4/1 Acne Control Therapy Pads are for use on the skin only. Do not get Inova 4/1 Acne Control Therapy Pads in your eyes, on your eyelids or lips, or on the inside of your nose or mouth. If you get Inova 4/1 Acne Control Therapy Pads in your eyes, rinse right away with cool tap water.

  • Avoid applying Inova 4/1 Acne Control Therapy Pads to raw or irritated skin, including sunburns, or to open wounds.

  • Several weeks may pass before you see improvement in your acne. Continue to use Inova 4/1 Acne Control Therapy Pads for the full time recommended by your doctor. If your acne does not improve or if it gets worse, check with your doctor.

  • Talk with your doctor before you use any other medicines, special cleansers, aftershave, or cosmetics on your skin.

  • Inova 4/1 Acne Control Therapy Pads may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Inova 4/1 Acne Control Therapy Pads. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.

  • Inova 4/1 Acne Control Therapy Pads may cause bleaching. Avoid contact with hair, fabrics, or carpeting.

  • Inova 4/1 Acne Control Therapy Pads should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.

  • PREGNANCY and BREAST-FEEDING: It is not known if Inova 4/1 Acne Control Therapy Pads can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Inova 4/1 Acne Control Therapy Pads while you are pregnant. It is not known if Inova 4/1 Acne Control Therapy Pads are found in breast milk. If you are or will be breast-feeding while you use Inova 4/1 Acne Control Therapy Pads, check with your doctor. Discuss any possible risks to your baby.


Possible side effects of Inova 4/1 Acne Control Therapy Pads:


All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:



Dryness; feeling of warmth; mild irritation, itching, peeling, redness, or stinging.



Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; dizziness; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); excessive burning, itching, irritation, peeling, redness, or tenderness of your skin; extreme dryness; swelling.



This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.


See also: Inova 4/1 Acne Control Therapy side effects (in more detail)


If OVERDOSE is suspected:


Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include excessive scaling; redness; swelling.


Proper storage of Inova 4/1 Acne Control Therapy Pads:

Store at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store in a tightly closed container, away from heat and light. Do not freeze. Keep Inova 4/1 Acne Control Therapy Pads out of the reach of children and away from pets.


General information:


  • If you have any questions about Inova 4/1 Acne Control Therapy Pads, please talk with your doctor, pharmacist, or other health care provider.

  • Inova 4/1 Acne Control Therapy Pads are to be used only by the patient for whom it is prescribed. Do not share it with other people.

  • If your symptoms do not improve or if they become worse, check with your doctor.

  • Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Inova 4/1 Acne Control Therapy Pads. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.



Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Inova 4/1 Acne Control Therapy resources


  • Inova 4/1 Acne Control Therapy Side Effects (in more detail)
  • Inova 4/1 Acne Control Therapy Use in Pregnancy & Breastfeeding
  • Inova 4/1 Acne Control Therapy Drug Interactions
  • Inova 4/1 Acne Control Therapy Support Group
  • 1 Review for Inova 4/1 Acne Control Therapy - Add your own review/rating


Compare Inova 4/1 Acne Control Therapy with other medications


  • Acne

Recombinate recombinant


Generic Name: antihemophilic factor (recombinant) (ant ee hee moe FIL ik FAK tor (ree KOM bin ant))

Brand Names: Advate rAHF-PFM, Helixate FS, Kogenate FS, Kogenate FS with Bioset, Recombinate, Refacto, Xyntha, Xyntha Solofuse


What is recombinant antihemophilic factor?

Antihemophilic factor is a naturally occurring protein in the blood that helps blood to clot. A lack of antihemophilic factor VIII is the cause of hemophilia A.


This medication works by temporarily raising levels of factor VIII in the blood to aid in clotting.


Recombinant antihemophilic factor is used to treat or prevent bleeding episodes in adults and children with hemophilia A. It is also used to control bleeding related to surgery or dentistry in a person with hemophilia, and to prevent joint damage in people age 16 or older with severe hemophilia A and no prior joint damage.


Recombinant antihemophilic factor is not for use in people with von Willebrand disease.

Recombinant antihemophilic factor may also be used for purposes not listed in this medication guide.


What is the most important information I should know about recombinant antihemophilic factor?


Do not use this medication if you have ever had a severe allergic reaction to antihemophilic factor in the past, or if you are allergic to mouse or beef proteins.

Before using recombinant antihemophilic factor, your specific blood clotting disorder must be diagnosed as factor VIII deficiency. Human antihemophilic factor will not treat von Willebrand disease.


Your body may develop antibodies to this medication, making it less effective. Call your doctor if this medicine seems to be less effective in controlling your bleeding.


To be sure this medication is helping your condition and is not causing harmful effects, your blood may need to be tested often. Visit your doctor regularly.


Wear a medical alert tag or carry an ID card stating that you have hemophilia. Any doctor, dentist, or emergency medical care provider who treats you should know that you have a bleeding or blood-clotting disorder.

What should I discuss with my health care provider before using recombinant antihemophilic factor?


Do not use this medication if you have ever had a severe allergic reaction to antihemophilic factor in the past, or if you are allergic to mouse or beef proteins.

Before using recombinant antihemophilic factor, your specific blood clotting disorder must be diagnosed as factor VIII deficiency. Recombinant antihemophilic factor will not treat von Willebrand disease.


FDA pregnancy category C. It is not known whether recombinant antihemophilic factor will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether recombinant antihemophilic factor passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I use recombinant antihemophilic factor?


Use exactly as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label. Always check the strength of the medicine on the label to be sure you are using the correct potency.


Recombinant antihemophilic factor is injected into a vein through an IV. You may be shown how to use an IV at home. Do not self-inject this medicine if you do not fully understand how to give the injection and properly dispose of used needles, IV tubing, and other items used to inject the medicine.


This medication comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.


Always wash your hands before preparing and giving your injection.

Recombinant antihemophilic factor must be mixed with a liquid (diluent) before injecting it. If you store your medicine in the refrigerator, take a medicine and diluent vial out of the refrigerator and allow each to reach room temperature before mixing them.


Gently swirl the medicine and diluent to mix them and allow the medicine to completely dissolve.


After mixing the medicine and diluent, the mixture should be kept at room temperature and must be used within 3 hours. Do not put mixed medicine into the refrigerator.

Prepare your dose in a syringe only when you are ready to give yourself an injection. Each vial is for one use only. After measuring your dose, throw the vial away, even if there is medicine left in it.


Do not use the medication if it has changed colors or has particles in it. Call your doctor for a new prescription.


Use each disposable needle only one time. Throw away used needles in a puncture-proof container (ask your pharmacist where you can get one and how to dispose of it). Keep this container out of the reach of children and pets.


Recombinant antihemophilic factor is usually given every 8 to 24 hours for 1 to 4 days, depending on the reason you are using the medication.


To be sure this medication is helping your condition and is not causing harmful effects, your blood may need to be tested often. Visit your doctor regularly.


Your body may develop antibodies to antihemophilic factor, making it less effective. Call your doctor if this medicine seems to be less effective in controlling your bleeding.


Wear a medical alert tag or carry an ID card stating that you have hemophilia. Any doctor, dentist, or emergency medical care provider who treats you should know that you have a bleeding or blood-clotting disorder. Store the medication and the diluent in the refrigerator and do not allow them to freeze. You may also store the medication and diluent at room temperature until the expiration date on the label. Some brands of this medicine can be stored at room temperature for only a certain number of months, or until the expiration date (whichever comes first). Follow the storage directions on the medicine label.

Do not store this medicine in bright light. Throw away any leftover medicine and diluent if the expiration date has passed.


What happens if I miss a dose?


Recombinant antihemophilic factor is sometimes used only as needed, so you may not be on a dosing schedule. If you are taking the medication regularly, use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.


What happens if I overdose?


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using recombinant antihemophilic factor?


Follow your doctor's instructions about any restrictions on food, beverages, or activity.


Recombinant antihemophilic factor side effects


Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; feeling light-headed, fainting; swelling of your face, lips, tongue, or throat. Stop using recombinant antihemophilic factor and call your doctor at once if you have a serious side effect such as:

  • chest pain;




  • easy bruising, increased bleeding episodes; or




  • bleeding from a wound or where the medicine was injected.



Less serious side effects may include:



  • sore throat, cough, runny nose;




  • fever or chills;




  • mild nausea, vomiting;




  • unusual or unpleasant taste in your mouth;




  • skin itching or rash;




  • warmth, redness, itching, or tingling under your skin;




  • joint pain or swelling;




  • dizziness;




  • headache; or




  • swelling, stinging, or irritation where the injection was given.



This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.


What other drugs will affect recombinant antihemophilic factor?


There may be other drugs that can interact with recombinant antihemophilic factor. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.



More Recombinate resources


  • Recombinate Side Effects (in more detail)
  • Recombinate Use in Pregnancy & Breastfeeding
  • Recombinate Support Group
  • 0 Reviews for Recombinate - Add your own review/rating


Compare Recombinate with other medications


  • Hemophilia A


Where can I get more information?


  • Your pharmacist can provide more information about recombinant antihemophilic factor.

See also: Recombinate side effects (in more detail)